Botox Users Warned of Rising Botulism Cases in UK

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UK Health Security Agency (UKHSA) continues to warn people to be aware of the signs and symptoms of botulism following adverse reactions after receiving cosmetic procedures involving botulinum toxin.

The number of clinically confirmed cases of iatrogenic botulism reported between 4 June and 6 August 2025 is now 41.

Cases have been reported in the:

  • North East

  • East Midlands

  • East of England

  • North West

  • Yorkshire and Humber

Investigations are ongoing but evidence so far suggests the use of an unlicensed Botox-like product.

Reactions have included:

  • difficulty swallowing

  • slurred speech

  • breathing difficulty requiring respiratory support

UKHSAhas issued national advice to clinicians to ensure that they look out for botulism in people who may have had a recent aesthetic procedure. This is to provide them with appropriate treatments, which can include giving anti-toxin.

UKHSAcontinues to advise people to take precautions when seeking aesthetic procedures, including checking if the product being used is licensed. Members of the public should also be advised not to purchase products from websites for self-administration.

Dr Gauri Godbole, Consultant Medical Microbiologist at UKHSA, said:

We are working closely with our partners to reduce the public health risk and would advise people to make sure they take precautions when seeking aesthetic procedures.

Botulism related to aesthetic procedures is rare, but it can be serious. It is caused by toxins produced by the bacterium Clostridium botulinum. These toxins (but not the bacteria) are the active ingredient in ‘Botox’ and similar products.

Symptoms of botulism can take up to 4 weeks to develop and if you have had a recent botulinum toxin (Botox-like) treatment and are having symptoms such as difficulty swallowing or breathing, contact NHS 111 for further advice and seek treatment.

If you are considering having a cosmetic procedure, please make sure to check that your practitioner is using a licensed product. On the NHS website there is more information on what sensible steps you can take when finding a practitioner.

Dr Alison Cave,MHRAChief Safety Officer said:

Public safety is a top priority for theMHRA. Botulinum toxin is a prescription-only medicine and should only be sold or supplied in accordance with a prescription given by an appropriate practitioner such as a doctor or other qualified healthcare professional.

Buying botulinum toxin in any other circumstances significantly increases the risk of getting a product which is either falsified or not licensed for use in the UK. This means that there are no safeguards to ensure products meet theMHRA’s standards for quality and safety. As such, they can endanger the health of the people who take them.

Our Criminal Enforcement Unit works hard to identify those involved in the illegal trade in medicines and takes robust enforcement action where necessary. This can include criminal prosecution.